Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn’s Disease

Abnormal composition of intestinal bacteria —“dysbiosis”— is characteristic of Crohn’s disease. Disease treatments include dietary changes and immunosuppressive anti-TNFα antibodies as well as ancillary antibiotic therapy but their effects on microbiota composition are undetermined. Using shotgun me...

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Détails bibliographiques
Publié dans:Cell Host Microbe
Auteurs principaux: Lewis, James D., Chen, Eric Z., Baldassano, Robert N., Otley, Anthony R., Griffiths, Anne M., Lee, Dale, Bittinger, Kyle, Bailey, Aubrey, Friedman, Elliot S., Hoffmann, Christian, Albenberg, Lindsey, Sinha, Rohini, Compher, Charlene, Gilroy, Erin, Nessel, Lisa, Grant, Amy, Chehoud, Christel, Li, Hongzhe, Wu, Gary D., Bushman, Frederic D.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633303/
https://ncbi.nlm.nih.gov/pubmed/26468751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.09.008
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