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The Orthology Clause in the Next Generation Sequencing Era: Novel Reference Genes Identified by RNA-seq in Humans Improve Normalization of Neonatal Equine Ovary RT-qPCR Data

BACKGROUND: Vertebrate evolution is accompanied by a substantial conservation of transcriptional programs with more than a third of unique orthologous genes showing constrained levels of expression. Moreover, there are genes and exons exhibiting excellent expression stability according to RNA-seq da...

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Veröffentlicht in:PLoS One
Hauptverfasser: Scarlet, Dragos, Ertl, Reinhard, Aurich, Christine, Steinborn, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633174/
https://ncbi.nlm.nih.gov/pubmed/26536597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142122
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