Drug Transporter Genetic Variants Are Not Associated with TDF-Related Renal Dysfunction in Patients with HIV-1 Infection: A Pharmacogenetic Study

OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNP) of drug transporter proteins for TDF is a risk factor for TDF-related renal function decrement. METHODS: This study investigated the association between 3 SNPs (ABCC2–24, 1249, and ABCB1 2677), which are shown to be associated w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nishijima, Takeshi, Hayashida, Tsunefusa, Kurosawa, Takuma, Tanaka, Noriko, Oka, Shinichi, Gatanaga, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633171/
https://ncbi.nlm.nih.gov/pubmed/26535588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141931
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