Broadening of Virus-Specific CD8(+) T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV Controllers

Control of HIV replication is a rare immunological event, providing clues to understand the viral control mechanism. CD8(+) T-cell responses are crucial for virus control, but it is unclear whether lasting HIV containment can be achieved after establishment of infection. Here, we describe lasting SI...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Nomura, Takushi, Yamamoto, Hiroyuki, Ishii, Hiroshi, Akari, Hirofumi, Naruse, Taeko K., Kimura, Akinori, Matano, Tetsuro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633064/
https://ncbi.nlm.nih.gov/pubmed/26536034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005247
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