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Activated estrogen receptor-mitogen-activated protein kinases cross talk confer acquired resistance to lapatinib
BACKGROUND: The efficacy of lapatinib is limited by the development of acquired resistance. The aim of this study was to investigate the role of estrogen receptor (ER) signaling compensatory activation in acquired resistance to lapatinib in breast cancer cells BT474 and the related mechanism. METHOD...
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| Publicado no: | Thorac Cancer |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632920/ https://ncbi.nlm.nih.gov/pubmed/26557906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12239 |
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