Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems

Aptamers, which can be screened via systematic evolution of ligands by exponential enrichment (SELEX), are superior ligands for molecular recognition due to their high selectivity and affinity. The interest in the use of aptamers as ligands for targeted drug delivery has been increasing due to their...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Jiang, Feng, Liu, Biao, Lu, Jun, Li, Fangfei, Li, Defang, Liang, Chao, Dang, Lei, Liu, Jin, He, Bing, Atik Badshah, Shaikh, Lu, Cheng, He, Xiaojuan, Guo, Baosheng, Zhang, Xiao-Bing, Tan, Weihong, Lu, Aiping, Zhang, Ge
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632726/
https://ncbi.nlm.nih.gov/pubmed/26473828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161023784
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