The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth

PknB is an essential serine/threonine protein kinase required for mycobacterial cell division and cell-wall biosynthesis. Here we demonstrate that overexpression of the external PknB_PASTA domain in mycobacteria results in delayed regrowth, accumulation of elongated bacteria and increased sensitivit...

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Veröffentlicht in:Open Biol
Hauptverfasser: Turapov, Obolbek, Loraine, Jessica, Jenkins, Christopher H., Barthe, Philippe, McFeely, Daniel, Forti, Francesca, Ghisotti, Daniela, Hesek, Dusan, Lee, Mijoon, Bottrill, Andrew R., Vollmer, Waldemar, Mobashery, Shahriar, Cohen-Gonsaud, Martin, Mukamolova, Galina V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632501/
https://ncbi.nlm.nih.gov/pubmed/26136255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150025
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