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Implication of different domains of the Leishmania major metacaspase in cell death and autophagy

Metacaspases (MCAs) are cysteine peptidases expressed in plants, fungi and protozoa, with a caspase-like histidine–cysteine catalytic dyad, but differing from caspases, for example, in their substrate specificity. The role of MCAs is subject to debate: roles in cell cycle control, in cell death or e...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Casanova, M, Gonzalez, I J, Sprissler, C, Zalila, H, Dacher, M, Basmaciyan, L, Späth, G F, Azas, N, Fasel, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632311/
https://ncbi.nlm.nih.gov/pubmed/26492367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.288
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