A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression.

Tyrosine hydroxylase (TH) catalyzes the conversion of L-tyrosine to 3,4-dihydroxy-L-phenylalanine, the first and rate-limiting step in catecholamine biosynthesis. The cAMP-dependent protein kinase (PKA) phosphorylates and activates the TH enzyme and is thought to mediate transcriptional induction of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kim, K S, Park, D H, Wessel, T C, Song, B, Wagner, J A, Joh, T H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7682705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3471
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