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A new conceptual framework for investigating complex genetic disease

Some common diseases are known to have an inherited component, however, their population- and familial-incidence patterns do not conform to any known monogenic Mendelian pattern of inheritance and instead they are currently much better explained if an underlying polygenic architecture is posited. St...

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Detalles Bibliográficos
Publicado en:Front Genet
Autor Principal: Hussain, Shobbir
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631989/
https://ncbi.nlm.nih.gov/pubmed/26583033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00327
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