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Mechanical strain determines the axis of planar polarity in ciliated epithelia

Epithelia containing multiciliated cells align beating cilia along a common planar axis specified by the conserved planar cell polarity (PCP) pathway. Specification of the planar axis is also thought to require a long-range cue to align the axis globally, but the nature of this cue in ciliated and o...

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Publicat a:Curr Biol
Autors principals: Chien, Yuan-Hung, Keller, Ray, Kintner, Chris, Shook, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631806/
https://ncbi.nlm.nih.gov/pubmed/26441348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.09.015
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