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Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study

AIMS/HYPOTHESIS: Statins and niacin (nicotinic acid) reduce circulating LDL-cholesterol (LDLC) levels by different mechanisms. Yet, both increase the risk of diabetes mellitus. Our objective was to relate blood LDL-C concentrations and a genetic risk score (GRS) for LDLC to the risk of incident diab...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Andersson, Charlotte, Lyass, Asya, Larson, Martin G., Robins, Sander J., Vasan, Ramachandran S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631796/
https://ncbi.nlm.nih.gov/pubmed/26409460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3762-x
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