Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

Staphylococcus aureus necrotizing pneumonia is recognized as a toxin-mediated disease, yet the tissue-destructive events remain elusive, partly as a result of lack of mechanistic studies in human lung tissue. In this study, a three-dimensional (3D) tissue model composed of human lung epithelial cell...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Mairpady Shambat, Srikanth, Chen, Puran, Nguyen Hoang, Anh Thu, Bergsten, Helena, Vandenesch, Francois, Siemens, Nikolai, Lina, Gerard, Monk, Ian R., Foster, Timothy J., Arakere, Gayathri, Svensson, Mattias, Norrby-Teglund, Anna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631791/
https://ncbi.nlm.nih.gov/pubmed/26398950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021923
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