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Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes

The Goto-Kakizaki (GK) rat, which has been developed by repeated inbreeding of glucose-intolerant Wistar rats, is the most widely studied rat model for Type 2 diabetes (T2D). However, the detailed genetic background of T2D phenotype in GK rats is still largely unknown. We report a survey of T2D susc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Tiancheng, Li, Hong, Ding, Guohui, Wang, Zhen, Chen, Yunqin, Liu, Lei, Li, Yuanyuan, Li, Yixue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631338/
https://ncbi.nlm.nih.gov/pubmed/26529237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141859
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