Impact of visceral leishmaniasis and curative chemotherapy on cytochrome P450 activity in Brazilian patients

AIMS: The aim of the present study was to investigate the impact of human visceral leishmaniasis (VL) and curative chemotherapy on the activity of cytochrome P450 (CYP) 3A, CYP2C9 and CYP2C19 in patients from an endemic region in Brazil. METHODS: Adult patients with parasitologically confirmed VL we...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Autores principales: Lanchote, Vera Lucia, Almeida, Roque, Barral, Aldina, Barral-Netto, Manoel, Marques, Maria Paula, Moraes, Natália V, da Silva, Angela M, Souza, Tania M V, Suarez-Kurtz, Guilherme
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Drug Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631188/
https://ncbi.nlm.nih.gov/pubmed/25940755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12677
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