Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women

BACKGROUND: Leptin (LEP) and adiponectin (ADIPOQ) genes encode adipokines that are mainly secreted by adipose tissues, involved in energy balance and suspected to play a role in the pathways linking adiposity to impaired glucose and insulin homeostasis. We have thus hypothesized that LEP and ADIPOQ...

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Détails bibliographiques
Publié dans:BMC Med Genet
Auteurs principaux: Houde, Andrée-Anne, Légaré, Cécilia, Biron, Simon, Lescelleur, Odette, Biertho, Laurent, Marceau, Simon, Tchernof, André, Vohl, Marie-Claude, Hivert, Marie-France, Bouchard, Luigi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631085/
https://ncbi.nlm.nih.gov/pubmed/25929254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0174-1
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