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Early activation of CD4+ and CD8+ T lymphocytes by myelin basic protein in subjects with MS

BACKGROUND: Multiple sclerosis is the most common autoimmune disorder affecting the central nervous system. In this study, whole blood samples were analyzed for activation capacity and the activatability of CD4+ and CD8+ T-lymphocytes by human total myelin basic protein (MBP), human MBP 104–118 frag...

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Pubblicato in:J Transl Med
Autore principale: Arneth, Borros
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630877/
https://ncbi.nlm.nih.gov/pubmed/26526848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0715-6
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