Reprogramming energy metabolism and inducing angiogenesis: co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas

BACKGROUND: Deregulation of cellular energetic metabolism was recently pointed out as a hallmark of cancer cells. This deregulation involves a metabolic reprogramming that leads to a high production of lactate. Lactate efflux, besides contributing for the glycolytic flux, also acts in the extracellu...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Pinheiro, Céline, Garcia, Eduardo A., Morais-Santos, Filipa, Moreira, Marise A. R., Almeida, Fábio M., Jubé, Luiz F., Queiroz, Geraldo S., Paula, Élbio C., Andreoli, Maria A., Villa, Luisa L., Longatto-Filho, Adhemar, Baltazar, Fátima
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630851/
https://ncbi.nlm.nih.gov/pubmed/26525902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1842-4
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