Insulin Therapy of Nondiabetic Septic Patients Is Predicted by para-Tyrosine/Phenylalanine Ratio and by Hydroxyl Radical-Derived Products of Phenylalanine

Hydroxyl radical converts Phe to para-, meta-, and ortho-Tyr (p-Tyr, m-Tyr, o-Tyr), while Phe is converted enzymatically to p-Tyr in the kidney and could serve as substrate for gluconeogenesis. Pathological isoforms m- and o-Tyr are supposed to be involved in development of hormone resistances. Role...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Kun, Szilárd, Molnár, Gergő A., Sélley, Eszter, Szélig, Lívia, Bogár, Lajos, Csontos, Csaba, Miseta, Attila, Wittmann, István
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630663/
https://ncbi.nlm.nih.gov/pubmed/26576228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/839748
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