The Plasmodium palmitoyl-S-acyl-transferase DHHC2 is essential for ookinete morphogenesis and malaria transmission

The post-translational addition of C-16 long chain fatty acids to protein cysteine residues is catalysed by palmitoyl-S-acyl-transferases (PAT) and affects the affinity of a modified protein for membranes and therefore its subcellular localisation. In apicomplexan parasites this reversible protein m...

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Udgivet i:Sci Rep
Main Authors: Santos, Jorge M., Kehrer, Jessica, Franke-Fayard, Blandine, Frischknecht, Friedrich, Janse, Chris J., Mair, Gunnar R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630622/
https://ncbi.nlm.nih.gov/pubmed/26526684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16034
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