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(13)C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

Altered tryptophan–kynurenine (KYN) metabolism has been implicated in major depressive disorder (MDD). The l-[1-(13)C]tryptophan breath test ((13)C-TBT) is a noninvasive, stable-isotope tracer method in which exhaled (13)CO(2) is attributable to tryptophan catabolism via the KYN pathway. We included...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ota, Miho, Hattori, Kotaro, Kajiwara, Masahiro, Higuchi, Teruhiko, Kunugi, Hiroshi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630584/
https://ncbi.nlm.nih.gov/pubmed/26524975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15994
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