(13)C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

Altered tryptophan–kynurenine (KYN) metabolism has been implicated in major depressive disorder (MDD). The l-[1-(13)C]tryptophan breath test ((13)C-TBT) is a noninvasive, stable-isotope tracer method in which exhaled (13)CO(2) is attributable to tryptophan catabolism via the KYN pathway. We included...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ota, Miho, Hattori, Kotaro, Kajiwara, Masahiro, Higuchi, Teruhiko, Kunugi, Hiroshi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630584/
https://ncbi.nlm.nih.gov/pubmed/26524975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15994
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