(13)C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

Altered tryptophan–kynurenine (KYN) metabolism has been implicated in major depressive disorder (MDD). The l-[1-(13)C]tryptophan breath test ((13)C-TBT) is a noninvasive, stable-isotope tracer method in which exhaled (13)CO(2) is attributable to tryptophan catabolism via the KYN pathway. We included...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ota, Miho, Hattori, Kotaro, Kajiwara, Masahiro, Higuchi, Teruhiko, Kunugi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630584/
https://ncbi.nlm.nih.gov/pubmed/26524975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15994
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