Chordoma: an update on the pathophysiology and molecular mechanisms

Chordoma is a rare low-grade primary malignant skeletal tumor, which is presumed to derive from notochord remnants. The pathogenesis of chordoma has not been fully elucidated. However, recent advances in the molecular biology studies have identified brachyury underlying the initiation and progressio...

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Bibliografiske detaljer
Udgivet i:Curr Rev Musculoskelet Med
Main Authors: Sun, Xin, Hornicek, Francis, Schwab, Joseph H.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Orthopedic Oncology: New Concepts and Techniques (JH Schwab, Section Editor)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630230/
https://ncbi.nlm.nih.gov/pubmed/26493697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12178-015-9311-x
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