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Chordoma: an update on the pathophysiology and molecular mechanisms

Chordoma is a rare low-grade primary malignant skeletal tumor, which is presumed to derive from notochord remnants. The pathogenesis of chordoma has not been fully elucidated. However, recent advances in the molecular biology studies have identified brachyury underlying the initiation and progressio...

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Detalhes bibliográficos
Publicado no:Curr Rev Musculoskelet Med
Main Authors: Sun, Xin, Hornicek, Francis, Schwab, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630230/
https://ncbi.nlm.nih.gov/pubmed/26493697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12178-015-9311-x
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