Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys

PURPOSE: To translate a recombinant peptide containing the amino-terminal fragment (ATF) of urokinase plasminogen activator receptor-targeted magnetic iron oxide (IO) nanoparticles (uPAR-targeted human ATF-IONPs) into clinical applications, we conducted a pilot study to evaluate the toxicity and pha...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Chen, Yushu, Gong, Li, Gao, Ning, Liao, Jichun, Sun, Jiayu, Wang, Yuqing, Wang, Lei, Zhu, Pengjin, Fan, Qing, Wang, Yongqiang Andrew, Zeng, Wen, Mao, Hui, Yang, Lily, Gao, Fabao
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630189/
https://ncbi.nlm.nih.gov/pubmed/26604745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S90587
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