Synergistic Actions of Blocking Angiopoietin-2 and Tumor Necrosis Factor-α in Suppressing Remodeling of Blood Vessels and Lymphatics in Airway Inflammation

Remodeling of blood vessels and lymphatics are prominent features of sustained inflammation. Angiopoietin-2 (Ang2)/Tie2 receptor signaling and tumor necrosis factor-α (TNF)/TNF receptor signaling are known to contribute to these changes in airway inflammation after Mycoplasma pulmonis infection in m...

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Publicat a:Am J Pathol
Autors principals: Le, Catherine T.K., Laidlaw, Grace, Morehouse, Christopher A., Naiman, Brian, Brohawn, Philip, Mustelin, Tomas, Connor, Jane R., McDonald, Donald M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2015
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630170/
https://ncbi.nlm.nih.gov/pubmed/26348576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.07.010
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