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Resveratrol Inhibits Hypoxia-Induced Vascular Endothelial Growth Factor Expression and Pathological Neovascularization

PURPOSE: To investigate the effects of resveratrol on the expression of hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) in human adult retinal pigment epithelial (ARPE-19) cells, and on experimental choroidal neovascularization (CNV) in mice. MATERIALS AND METHODS:...

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Publicado en:Yonsei Med J
Main Authors: Lee, Christopher Seungkyu, Choi, Eun Young, Lee, Sung Chul, Koh, Hyoung Jun, Lee, Joon Haeng, Chung, Ji Hyung
Formato: Artigo
Idioma:Inglês
Publicado: Yonsei University College of Medicine 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630060/
https://ncbi.nlm.nih.gov/pubmed/26446654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2015.56.6.1678
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