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Novel applications of statins for bone regeneration

The use of statins for bone regeneration is a promising and growing area of research. Statins, originally developed to treat high cholesterol, are inhibitors of the enzyme 3-hydroxy-3-methylglutaryl, the rate-limiting enzyme of the mevalonate pathway. Because the mevalonate pathway is responsible fo...

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Pubblicato in:Natl Sci Rev
Autori principali: Shah, Sarita R., Werlang, Caroline A., Kasper, F. Kurtis, Mikos, Antonios G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630027/
https://ncbi.nlm.nih.gov/pubmed/26543666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwu028
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