The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

IgE-mediated activation of mast cells and basophils contributes to protective immunity against helminths but also causes allergic responses. The development and persistence of IgE responses are poorly understood, which is in part due to the low number of IgE-producing cells. Here, we used next gener...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Turqueti-Neves, Adriana, Otte, Manuel, Schwartz, Christian, Schmitt, Michaela Erika Renate, Lindner, Cornelia, Pabst, Oliver, Yu, Philipp, Voehringer, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629909/
https://ncbi.nlm.nih.gov/pubmed/26523376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002290
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