The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

IgE-mediated activation of mast cells and basophils contributes to protective immunity against helminths but also causes allergic responses. The development and persistence of IgE responses are poorly understood, which is in part due to the low number of IgE-producing cells. Here, we used next gener...

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Udgivet i:PLoS Biol
Main Authors: Turqueti-Neves, Adriana, Otte, Manuel, Schwartz, Christian, Schmitt, Michaela Erika Renate, Lindner, Cornelia, Pabst, Oliver, Yu, Philipp, Voehringer, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629909/
https://ncbi.nlm.nih.gov/pubmed/26523376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002290
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