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Upregulation of cytosolic phosphoenolpyruvate carboxykinase is a critical metabolic event in melanoma cells that repopulate tumors

While metabolic defects have been investigated extensively in differentiated tumor cells, much less attention has been directed to the metabolic properties of stem-like cells that repopulate tumors (tumor-repopulating cells [TRC]). Here we show that melanoma TRCs cultured in 3D soft fibrin gels repr...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Li, Yong, Luo, Shunqun, Ma, Ruihua, Liu, Jing, Xu, Pingwei, Zhang, Huafeng, Tang, Ke, Ma, Junwei, Zhang, Yi, Liang, Xiaoyu, Sun, Yanling, Ji, Tiantian, Wang, Ning, Huang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629827/
https://ncbi.nlm.nih.gov/pubmed/25712344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2615
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