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Pulsed high intensity focused ultrasound (pHIFU) enhances delivery of doxorubicin in a preclinical model of pancreatic cancer

Pancreatic cancer is characterized by extensive stromal desmoplasia which decreases blood perfusion and impedes chemotherapy delivery. Breaking the stromal barrier could both increase perfusion and permeabilize the tumor, enhancing chemotherapy penetration. Mechanical disruption of the stroma can be...

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Foilsithe in:Cancer Res
Main Authors: Li, Tong, Wang, Yak-Nam, Khokhlova, Tatiana D., D’Andrea, Samantha, Starr, Frank, Chen, Hong, McCune, Jeannine S., Risler, Linda J., Mashadi-Hossein, Afshin, Hwang, Joo Ha
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629806/
https://ncbi.nlm.nih.gov/pubmed/26216548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0296
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