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Methotrexate as an oral corticosteroid-sparing agent in severe asthma: the emergence of a responder asthma endotype

BACKGROUND: Sustained use of oral corticosteroids is associated with significant side effects. It is therefore of interest to find a corticosteroid-sparing agent. In two meta-analyses, methotrexate resulted in a rather small reduction in the oral corticosteroid maintenance dose. We have used methotr...

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Publicat a:Eur Clin Respir J
Autors principals: Knarborg, Malene, Hilberg, Ole, Hoffmann, Hans-Jürgen, Dahl, Ronald
Format: Artigo
Idioma:Inglês
Publicat: Co-Action Publishing 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629721/
https://ncbi.nlm.nih.gov/pubmed/26557239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/ecrj.v1.25037
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