Measles Virus Epitope Presentation by HLA: Novel Insights into Epitope Selection, Dominance, and Microvariation

Immunity to infections with measles virus (MV) can involve vigorous human leukocyte antigen (HLA) class I-restricted CD8(+) cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome. To address which regions of the MV proteome are...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schellens, Ingrid M., Meiring, Hugo D., Hoof, Ilka, Spijkers, Sanne N., Poelen, Martien C. M., van Gaans-van den Brink, Jacqueline A. M., Costa, Ana I., Vennema, Harry, Keşmir, Can, van Baarle, Debbie, van Els, Cécile A. C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629467/
https://ncbi.nlm.nih.gov/pubmed/26579122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00546
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