Construction of CTLA-4-Ig Fusion Gene in pBudCE4.1 Expression Vector

BACKGROUND: CTLA-4 inhibitory signals prevent cell cycle progression and IL-2 production, leading to a halt on an ongoing immune response. CTLA4-Ig fusion proteins contain the extracellular domain of CTLA-4 and Fc fragment of human IgG antibody. In this study we aimed to fuse the ctla-4 gene encodin...

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Bibliografiske detaljer
Udgivet i:Avicenna J Med Biotechnol
Main Authors: Yazdanpanah-Samani, Mahsa, Mahmoudi Maymand, Elham, Jahangeerfam, Tayebeh, Ghaderi, Abbas
Format: Artigo
Sprog:Inglês
Udgivet: Avicenna Research Institute 2015
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Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629461/
https://ncbi.nlm.nih.gov/pubmed/26605013
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