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Calycosin-7-O-β-d-glucopyranoside stimulates osteoblast differentiation through regulating the BMP/WNT signaling pathways

The isoflavone calycosin-7-O-β-d-glucopyranoside (CG) is a principal constituent of Astragalus membranaceus (AR) and has been reported to inhibit osteoclast development in vitro and bone loss in vivo. The aim of this study was to investigate the osteogenic effects of CG and its underlying mechanism...

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Bibliographic Details
Published in:Acta Pharm Sin B
Main Authors: Jian, Jing, Sun, Lijuan, Cheng, Xun, Hu, Xiaofang, Liang, Jichao, Chen, Yong
Format: Artigo
Language:Inglês
Published: Elsevier 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629440/
https://ncbi.nlm.nih.gov/pubmed/26579475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.06.005
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