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IL-7R signaling in regulatory T cells maintains peripheral and allograft tolerance in mice
Foxp3(+)CD4(+) regulatory T cells (T(reg)) have a crucial role in controlling CD4(+) T-cell activation, proliferation, and effector function. However, the molecular mechanisms regulating T(reg) function remain poorly understood. Here we assessed the role of IL-7, a key cytokine regulating T-cell hom...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629352/ https://ncbi.nlm.nih.gov/pubmed/26450881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510045112 |
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