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Synthesis and antiviral activity of a series of novel N-phenylbenzamide and N-phenylacetophenone compounds as anti-HCV and anti-EV71 agents

A series of novel N-phenylbenzamide and N-phenylacetophenone compounds were synthesized and evaluated for their antiviral activity against HCV and EV71 (strain SZ-98). The biological results showed that three compounds (23, 25 and 41) exhibited considerable anti-HCV activity (IC(50)=0.57–7.12 μmol/L...

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Vydáno v:Acta Pharm Sin B
Hlavní autoři: Jiang, Zhi, Wang, Huiqiang, Li, Yanping, Peng, Zonggen, Li, Yuhuan, Li, Zhuorong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629265/
https://ncbi.nlm.nih.gov/pubmed/26579447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.03.013
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