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Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment

The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression. RNA interference mediated by siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific mRNAs. Therefore, c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharm Sin B
Hauptverfasser: Kang, Lin, Gao, Zhonggao, Huang, Wei, Jin, Mingji, Wang, Qiming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629232/
https://ncbi.nlm.nih.gov/pubmed/26579443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.03.001
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