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Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia
Inflammatory signal-mediated release of high-mobility group box 1 (HMGB1) is a damage-associated molecular pattern or alarmin. The inflammatory functions of HMGB1 have been extensively investigated; however, less is known about the mechanisms controlling HMGB1 release. We show that SIRT1, the human...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629154/ https://ncbi.nlm.nih.gov/pubmed/26522327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15971 |
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