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IL-10-producing CD4(+) T cells negatively regulate fucosylation of epithelial cells in the gut

Fucosylated glycans on the surface of epithelial cells (ECs) regulate intestinal homeostasis by serving as attachment receptors and a nutrient source for some species of bacteria. We show here that epithelial fucosylation in the ileum is negatively regulated by IL-10-producing CD4(+) T cells. The nu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Goto, Yoshiyuki, Lamichhane, Aayam, Kamioka, Mariko, Sato, Shintaro, Honda, Kenya, Kunisawa, Jun, Kiyono, Hiroshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629126/
https://ncbi.nlm.nih.gov/pubmed/26522513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15918
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