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Preclinical investigation of the pharmacokinetics, metabolism, and protein and red blood cell binding of DRDE-07: a prophylactic agent against sulphur mustard

DRDE-07, a newly synthesized amifostine analog currently under clinical investigation in a phase I trial, is a potent antidote against sulfur mustard toxicity. The purpose of this research was to evaluate the pharmacokinetic profile of DRDE-07 in female Swiss Albino mice after a single oral dose of...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Verma, Pankaj, Vijayaraghavan, Rajagopalan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629098/
https://ncbi.nlm.nih.gov/pubmed/26579409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2014.08.002
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