Nonbilayer Phospholipid Arrangements Are Toll-Like Receptor-2/6 and TLR-4 Agonists and Trigger Inflammation in a Mouse Model Resembling Human Lupus

Systemic lupus erythematosus is characterized by dysregulated activation of T and B cells and autoantibodies to nuclear antigens and, in some cases, lipid antigens. Liposomes with nonbilayer phospholipid arrangements induce a disease resembling human lupus in mice, including IgM and IgG antibodies a...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Wong-Baeza, Carlos, Tescucano, Alonso, Astudillo, Horacio, Reséndiz, Albany, Landa, Carla, España, Luis, Serafín-López, Jeanet, Estrada-García, Iris, Estrada-Parra, Sergio, Flores-Romo, Leopoldo, Wong, Carlos, Baeza, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629040/
https://ncbi.nlm.nih.gov/pubmed/26568960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/369462
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