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Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

Consumption of a protein-containing meal by a fasted animal promotes protein accretion in skeletal muscle, in part through leucine stimulation of protein synthesis and indirectly through repression of protein degradation mediated by its metabolite, α-ketoisocaproate. Mice lacking the mitochondrial b...

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Vydáno v:Physiol Genomics
Hlavní autoři: Lynch, Christopher J., Kimball, Scot R., Xu, Yuping, Salzberg, Anna C., Kawasawa, Yuka Imamura
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629004/
https://ncbi.nlm.nih.gov/pubmed/26351290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00055.2015
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