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Endothelial-derived hyperpolarization contributes to acetylcholine-mediated vasodilation in human skin in a dose-dependent manner

Cutaneous acetylcholine (ACh)-mediated dilation is commonly used to assess microvascular function, but the mechanisms of dilation are poorly understood. Depending on dose and method of administration, nitric oxide (NO) and prostanoids are involved to varying extents and the roles of endothelial-deri...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Brunt, Vienna E., Fujii, Naoto, Minson, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628993/
https://ncbi.nlm.nih.gov/pubmed/26384409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00201.2015
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