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How do persistent infections with hepatitis C virus cause liver cancer?

Persistent infection with hepatitis C virus (HCV) is associated with an increased risk of hepatocellular carcinoma (HCC). Cancer typically develops in a setting of chronic hepatic inflammation and advanced fibrosis or cirrhosis, and such tissue represents a pre-neoplastic “cancer field”. However, no...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Mitchell, Jonathan, Lemon, Stanley M., McGivern, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628866/
https://ncbi.nlm.nih.gov/pubmed/26426687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2015.09.003
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