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Redox-Sensitive Nanoparticles from Amphiphilic Cholesterol-Based Block Copolymers for Enhanced Tumor Intracellular Release of Doxorubicin

A novel amphiphilic cholesterol-based block copolymer comprised of a polymethacrylate bearing cholesterol block and a polyethylene glycol block with reducible disulfide bonds (PC5MA-SS-PEO) was synthesized and evaluated as a redox-sensitive nanoparticulate delivery system. The self-assembled PC5MA-S...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Nguyen, Chi Thanh, Tran, Thanh Huyen, Amiji, Mansoor, Lu, Xiuling, Kasi, Rajeswari M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628861/
https://ncbi.nlm.nih.gov/pubmed/26169153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.06.011
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