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Differential regulation of matrix metalloproteinases in varicella zoster virus-infected human brain vascular adventitial fibroblasts

Upon reactivation, varicella zoster virus (VZV) spreads transaxonally, infects cerebral arteries and causes ischemic or hemorrhagic stroke, as well as aneurysms. The mechanism(s) of VZV-induced aneurysm formation is unknown. However, matrix metalloproteinases (MMPs), which digest extracellular struc...

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Bibliografiske detaljer
Udgivet i:J Neurol Sci
Main Authors: Nagel, Maria A., Choe, Alexander, Rempel, April, Wyborny, Ann, Stenmark, Kurt, Gilden, Don
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628845/
https://ncbi.nlm.nih.gov/pubmed/26443282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2015.09.349
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