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Chemical Hypoxia Brings to Light Altered Autocrine Sphingosine-1-Phosphate Signalling in Rheumatoid Arthritis Synovial Fibroblasts
Emerging evidence suggests a role for sphingosine-1-phosphate (S1P) in various aspects of rheumatoid arthritis (RA) pathogenesis. In this study we compared the effect of chemical hypoxia induced by cobalt chloride (CoCl(2)) on the expression of S1P metabolic enzymes and cytokine/chemokine secretion...
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| Publicado no: | Mediators Inflamm |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628658/ https://ncbi.nlm.nih.gov/pubmed/26556954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/436525 |
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