Enhanced in vitro osteogenic differentiation of human fetal MSCs attached to 3D microcarriers versus harvested from 2D monolayers

BACKGROUND: Mesenchymal stem cells (MSCs) are of great interest in bone regenerative medicine due to their osteogenic potential and trophic effects. However, challenges to large-scale production of MSCs can hinder the translation of MSC therapies. 3D Microcarrier (MC)-based MSC culture presents a sc...

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Pubblicato in:BMC Biotechnol
Autori principali: Shekaran, Asha, Sim, Eileen, Tan, Kah Yong, Chan, Jerry Kok Yen, Choolani, Mahesh, Reuveny, Shaul, Oh, Steve
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628389/
https://ncbi.nlm.nih.gov/pubmed/26520400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0219-8
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