Breast cancer metastasis suppressor 1 (BRMS1) attenuates TGF-β1-induced breast cancer cell aggressiveness through downregulating HIF-1α expression

BACKGROUND: Cancer metastasis is a multi-step event including epithelial-to-mesenchymal transition (EMT). Breast cancer metastasis suppressor 1 (BRMS1) is a novel metastasis suppressor protein without anti-proliferating activity. However, a detailed underlying mechanism by which BRMS1 attenuates can...

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Publicado en:BMC Cancer
Autores principales: Cho, Kyung Hwa, Yu, Seong-Lan, Cho, Do Yeun, Park, Chang Gyo, Lee, Hoi Young
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628375/
https://ncbi.nlm.nih.gov/pubmed/26520789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1864-y
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