Cytosolic phospholipase A(2) plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway

BACKGROUND: Oxidative stress and inflammation are important factors contributing to the pathophysiology of numerous neurological disorders, including Alzheimer’s disease, Parkinson’s disease, acute stroke, and infections of the brain. There is well-established evidence that proinflammatory cytokines...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Chuang, Dennis Y., Simonyi, Agnes, Kotzbauer, Paul T., Gu, Zezong, Sun, Grace Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628268/
https://ncbi.nlm.nih.gov/pubmed/26520095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0419-0
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