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HMMvar-func: a new method for predicting the functional outcome of genetic variants

BACKGROUND: Numerous tools have been developed to predict the fitness effects (i.e., neutral, deleterious, or beneficial) of genetic variants on corresponding proteins. However, prediction in terms of whether a variant causes the variant bearing protein to lose the original function or gain new func...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Liu, Mingming, Watson, Layne T., Zhang, Liqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628267/
https://ncbi.nlm.nih.gov/pubmed/26518340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0781-z
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